Sihai network

Understanding of the etiology of coronary heart disease

A large number of epidemiological studies on coronary atherosclerotic heart disease have shown that the following factors are closely related to the incidence of coronary heart disease. These factors are known as the risk factors of coronary heart disease

1. Age the disease is more common in people over 40 years old. The incidence of atherosclerosis can start in children, and the incidence rate of coronary heart disease increases with age.

2. gender is more common among men, and the incidence rate of male and female is about 2: 1. Because estrogen has anti atherosclerosis effects, the incidence rate of women in the post term period is increasing rapidly.

3. family history has coronary heart disease, hypertension, family history, and the incidence rate of coronary heart disease is increasing.

4. Individuals with type a personality (competitive and competitive) have a higher prevalence of coronary heart disease, and people with mental stress are also prone to the disease. It may be related to the high concentration of catecholamines in vivo for a long time.

5. Smoking is an important risk factor of coronary heart disease. The prevalence of coronary heart disease in smokers is 5 times higher than that in non-smokers, and it is directly proportional to the amount of smoking. Smoking in the blood of carbon monoxide and hemoglobin increased, nicotine in cigarette constricted blood vessels, resulting in arterial wall hypoxia and arterial damage.

6. Hypertension is an important risk factor of coronary heart disease. Hypertension patients with coronary heart disease are 4 times more than those with normal blood pressure. 60% - 70% of patients with coronary heart disease have hypertension. At the same time, the increase of blood pressure promotes the infiltration of plasma lipids into vascular intimal cells, which leads to platelet aggregation and smooth muscle cell proliferation and atherosclerosis.