Vigilance! Often take morpholine can cause menstruation abnormality. Let's take a look at specific cases.
Beijing reader Miss Li asked: my menstruation has been very normal, but in the last three months, it has been delayed for more than ten days every month. Compared with the past, the only difference I have recently is that I have been taking domperidone. I wonder if it has anything to do with taking medicine?
Professor Sun Rongxi, chief gynecologist of Jiangsu Provincial People's Hospital, standing member of digestive branch of Chinese Medical Association, and Professor Sun Tao, Department of Gastroenterology of PLA Navy General Hospital, a: modoline is a new generation of gastric motility drug. It can antagonize peripheral dopamine receptors, enhance gastric peristalsis, promote gastric emptying, coordinate gastric and duodenal movements, and is commonly used in flatulence and dyspepsia.
The phenomenon of postponing menstruation after taking domperidone did occur in clinic, which may be caused by its inhibition of central dopamine receptor. Once the central dopamine receptor is inhibited, the amount of hypothalamic releasing factor entering the anterior pituitary will be reduced, and the secretion of gonadotropin and corticotropin will also be reduced accordingly, resulting in menopause or delayed ovulation.
Once this happens, there is no need to worry too much. The abnormal menstruation caused by domperidone is not harmful to the body.
Women's normal menstrual cycle is generally 28-30 days, and it is normal to advance or postpone one week. Appear amenorrhea or delay, want to stop drug only, can restore normal menstrual cycle. If there is abnormal menstruation, should be timely to the hospital for examination. In addition, the general use of domperidone should not be more than 1 month, symptoms improved, the best drug withdrawal.