Recently, the news that Wang Hong killed fish brother and killed himself by drinking paraquat has spread wildly to the Internet. While people are exploring the truth, many people are also curious about what drug is paraquat? Is there an antidote for paraquat? Let's take a look.
What is Paraquat
It is a kind of pesticide, especially toxic. It is generally used for the treatment of crop insect disease. When it is used, it needs to take anti-virus measures.
Paraquat, whose chemical name is 1-1-dimethyl4-4-bipyridine cation salt, is a kind of fast inactivating herbicide with contact killing effect and certain internal absorption effect. It can be quickly absorbed by green tissue of plants and make them wither. It has no effect on non green organizations. It is not effective to plant roots, perennial underground stems and perennial roots.
Paraquat is very toxic to human beings, and there is no specific antidote. The death rate of oral poisoning is very high. At present, it has been banned or strictly restricted by more than 20 countries. Since July 1, 2014, China has revoked the registration and production license of Baicao low-water agent, and stopped production; however, the water agent of the mother drug manufacturer has been kept for export registration and allowed to be exclusively used for export production, and the sale and use of water agent in China has been stopped on July 1, 2016.
Moderate toxicity. However, it does great harm to human organs and has no specific antidote. The death rate of oral poisoning can reach more than 90%. At present, it has been banned or strictly restricted by more than 20 countries. The acute oral LD50 was 150 mg / kg in rats and 204 mg / kg in rabbits. It can irritate the eyes and cause nail and skin ulceration; oral administration of 3 G can lead to systemic poisoning and lead to multiple organ failure such as liver and kidney, pulmonary fibrosis (irreversible) and respiratory failure. It is easy to misdiagnose or neglect the condition because the symptoms are not obvious in the golden period of pre poisoning treatment.
Dosage form: there are 200g / L water agent and 250G / L water agent. This product has two kinds of dichloride and bisulfate.
Does paraquat have an antidote
There is no antidote, which is very harmful to people.
At present, there is no specific antidote. First, maintain the acid-base balance in the body, and then fear organ failure. Do not inhale oxygen until you have to. Most patients died of respiratory distress syndrome.
Paraquat is very toxic. The damage to the important organs of the whole body is very serious, and the mortality rate is very high. Due to the uncertainty of disease changes, there is no uniform time paraquat in the risk period, and the most common trade name is gram without trace. It is a strong weed killing herbicide, which has a strong toxic effect on human and animal. Most of them are poisoned by taking it by mistake or taking it by suicide, but they can also be absorbed by skin and breath to death.
Suggestions: after taking paraquat by mistake, we must rescue it as soon as possible. 1. Wash the stomach fully as soon as possible and accelerate the excretion. At present, there is no effective antidote for paraquat poisoning. 2. To prevent the formation of oxygen free radicals and reduce the damage to the cell membrane structure, we should use superoxide dismutase, paraquat monoclonal antibody, large dose vitamin C and E as soon as possible. 3. Use the ventilator as early as possible. In order to increase gas exchange, improve oxygenation function, improve oxygen partial pressure and reduce lung injury. 4. Conduct hemoperfusion as early as possible. It has been proved by experience that patients who have not been perfused for more than 48 hours have serious damage to lung, liver and stomach, and finally die of multiple organ failure.
Notes on Paraquat
1. In order to arouse people's vigilance, paraquat's medicine liquid is added with odorant. If the liquid you unscrew smells, it is likely to be paraquat.
2. Spray alcohol evenly and thoughtfully. Add 0.1% washing powder into the liquid medicine to improve the adhesion of the liquid medicine. The efficacy of the medicine can be basically guaranteed in case of rain 30 minutes after application.
3. The clinical manifestations are contact dermatitis and chemical burn of mucous membrane, such as skin erythema, blister, ulcer, etc., conjunctiva and cornea burn to form ulcer, even perforation. Long term and large-scale contact may cause systemic damage or even life-threatening.
4. Paraquat is an inactivating herbicide, which is used in the garden and crop growth period. Do not pollute the crops to avoid drug damage.
5. It is not effective to plant roots, perennial underground stems and perennial roots. Paraquat is very toxic to people, and there is no specific medicine. The death rate of oral poisoning can reach more than 90%. At present, paraquat has been banned or strictly restricted by more than 20 countries.
6. Protective measures shall be taken during dispensing and spraying. Rubber gloves, masks and work clothes shall be worn. If liquid medicine splashes into eyes or skin, wash immediately.