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What are the factors leading to cirrhosis?

What are the factors leading to cirrhosis? What are the causes of cirrhosis? The main cause of ascites in cirrhosis is portal hypertension, which is also an important sign of decompensation of portal hypertension. Through the detection of the research surface, it was found that the ascites decreased after treatment, and the portal vein blood flow increased. Let's take a look at the relevant content.

Ascites rarely formed when the portal pressure was 12 mmHg. A retrospective study showed that devascularization was better than portosystemic shunt. The incidence of ascites in the former is much higher than that in the latter. Under the action of some vasoactive mediators, the splenic arterioles can be widely dilated, and the latter can increase the blood flow of portal vein. Therefore, even if collateral circulation is established, the portal pressure can still be significantly increased.

In addition, the increase of capillary pressure and lymphatic flow caused by chronic portal hypertension is also an important factor in the formation of ascites.

The relationship between portal hypertension and renal dysfunction and ascites formation is confirmed in the following three aspects at least

① Portal hypertension causes changes in the circulation of the spleen and the whole body, leading to the activation of angiotensin and the anti natriuretic system, and renal sodium retention.

② The increase of liver pressure leads to hepatorenal reflex and sodium water retention.

* the effect of sodium retention in the kidneys can be achieved through the portal shunting of substances in the spleen region.

After reading the above contents, we should have some understanding of the factors that lead to liver cirrhosis? What are the reasons for the formation of liver cirrhosis? What are the factors that lead to liver cirrhosis? What are the reasons for the formation of liver cirrhosis? Today we will introduce here. More topics about the treatment of liver cirrhosis will continue to be introduced in the following articles. Welcome to check. I wish you a happy life!