Does frequent smoking also lead to gastric ulcer? More and more data show that smoking is closely related to gastric ulcer, and ulcer is more common in smokers than in nonsmokers. Although smoking incidence rate is higher, it can not be concluded that smoking is the cause of ulcers, but smoking is a condition that causes ulcer deterioration or a condition for ulcers.
For example, the incidence rate of gastric ulcer in young women in Australia is quite high. It is believed that smoking has a great impact on smoking besides family history and aspirin. According to experiments, nicotine contained in cigarette can directly excite vagus nerve and increase gastric acid secretion; in addition, cigarette smoking can inhibit pancreatic secretion and cause abnormal phenomenon of pyloric sphincter insufficiency and duodenal juice flowing back into stomach, which has adverse effects on normal function of digestive system.
Reflux duodenal fluid, especially bile acid, can cause gastric mucosal injury and inflammation, which may be caused by bile damage to gastric mucosa. This causes hydrogen ions to penetrate and damage the gastric mucosa. Bile can also change the nature of gastric mucus, make its surface mucous membrane exfoliate, and make epithelial cells empty the mucus content. In addition, bile can also destroy the barrier of mucous membrane, so that it can no longer prevent hydrogen ion from penetrating into mucous membrane. The reverse diffusion of hydrogen ion causes further damage to mucous membrane. Bile can also destroy the surface epithelial cells and diffuse into the mucosa, stimulate mast cells to release histamine, increase the concentration of histamine in the gastric intercellular fluid, cause vasodilation, increase the mucosal blood flow and capillary permeability, and then cause mucosal edema, bleeding, inflammation and even ulceration.
A survey in North China showed that 58.6% of the patients with upper gastrointestinal ulcer were smokers. Therefore, while treating ulcer disease, patients should be advised to ban smoking, at least reduce the amount of smoking, so as to shorten the healing time of ulcer.
After reading the above content, we should have some understanding of the problem of whether regular smoking can also lead to gastric ulcer. Today we will introduce here. More topics about gastric function and health will be introduced in the following articles. Welcome to check. Wish you a happy life!