Can vagina also be allergic? Can pollen cause vagina allergy? Inhalation of pollen, latex condom, or even semen of sexual partners may cause vagina allergy, causing allergic vaginitis. Patients with allergic history of vaginitis should pay special attention to timely medical treatment and symptomatic treatment.
Can vagina also be allergic?
The characteristics of human vaginal mucosal blood flow may affect the concentration of various substances in the vagina, making these substances become local or systemic allergens. Semen composition, drugs and food taken by semen neutral partners, spermicide, soap, sanitary cotton, latex, intestinal parasites and Candida albicans may induce anaphylaxis. In addition, pollen, dust or food particles may be inadvertently carried into the vagina or even absorbed by the whole body. Many studies have shown that vaginal immune response leads to recurrent vaginitis in some patients. IgE antibodies against Candida albicans, semen components, pollen and contraceptive spermicides can be found in vaginal fluid, and eosinophils can be seen in vaginal smears in most cases.
Allergen selectively accumulates in the vaginal mucosa and transports antigen through the duct system. The mast cells degranulate and release histamine and other inflammatory mediators, resulting in allergic vaginitis.
Histamine is a potential inducer of macrophage prostaglandin, which induces the production of prostaglandin E2, which inhibits cellular immune response. The mechanism of antifungal resistance depends on cellular immunity. Therefore, as a result, Candida vaginitis is secondary to primary allergic vaginitis.
How to discover allergic vaginitis?
1. The main symptoms are increased vaginal secretions, purulent leucorrhea, rotten tissue discharge and odor.
2. Vaginal examination showed erosion and ulceration of vaginal mucosa. In patients with a long course of disease, extensive and hard scar adhesion could be formed in the vagina, resulting in vaginal stenosis or even atresia.
3. If there is vaginal, uterine hematocele, empyema, anal examination can touch the swollen vagina and swollen uterus.
4. The occurrence of symptoms has obvious correlation with systemic or local medication.
Doctors can make a diagnosis according to the history and clinical manifestations.
1. History detailed inquiry of history is very important for the diagnosis of allergic vaginitis. Pay attention to inquire about the course of the disease and the treatment in the past, and understand the possible inducing factors, such as personal cleaning habits, dressing habits, psychological state and so on. Whether there is a family history of allergy, because most of the patients allergic to inhalation, semen and Candida albicans have a family history of allergy and symptoms of other organ diseases, such as rhinitis, asthma and conjunctivitis. Children should also be aware of sanitary conditions and whether they have been sexually abused.
2. The clinical manifestations of adult women are pruritus, burning sensation of vulva, difficulty in sexual intercourse and vaginal discharge. Vaginal secretions may be clear and have Candida albicans infection. The secretions are like skimmed milk cheese. Vaginal vascular edema, acute or chronic inflammatory changes.
How does suffer from allergic vaginitis to do?
1. Medication:
(1) Antihistamines: the results of prophylactic use of antihistamines are reported differently, and few reports show that oral antihistamines are effective for allergic vaginitis. There is a lack of open and double-blind studies on antihistamine therapy.
(2) Cromoglycine: in some women with allergic vaginitis, local treatment with mast cell stabilizer can also slow down symptoms. Mild symptoms can be used before sexual intercourse, similar to antihistamines, but there is a lack of open and double-blind studies to prove its exact effect.
(3) Cortical alcohols: a case of failure in antihistamine treatment was reported, which could completely control the symptoms.
2. Immunotherapy
(1) Inhalation therapy: a series of reports suggest that inhalation therapy is one of the immunotherapies to relieve the symptoms of allergic vaginitis. It is mainly used for allergic reaction caused by pollen and house dust mite.
(2) Candida albicans: Moraes summarized the literature of 177 women with recurrent vaginal candidiasis who were treated with Candida albicans allergen. All patients had positive direct skin test for Candida albicans, and the remission rate of symptoms was 65% - 80%. All patients received the treatment because of other treatment failure. This treatment seems to be the only choice for this kind of patients, so there is a lack of double-blind comparative analysis of immunotherapy for Candida albicans.
(3) Human seminal plasma: subcutaneous immunotherapy with whole seminal plasma or semen fragments. Bernstein reported that this treatment was 100% successful. Transvaginal approach is another alternative. Before 1999, 3 cases of successful transvaginal desensitization with human seminal plasma were reported. Each course of treatment has a 3-day interval, and each course of treatment must maintain desensitization.
3. Management of patients with allergic reaction to seminal plasma, seminal plasma and latex
The management of seminal plasma hypersensitivity includes condom contraception, systemic antihistamines and transvaginal sodium cromoglycate pretreatment, which can be considered as immunotherapy with allergen protein from the seminal plasma of spouses. Immunotherapy is not recommended for patients with local reactions. Some women are allergic to semen and latex at the same time, and can use condoms made of sheep intestines, but this kind of condom can not prevent HIV infection. Men use double-layer condom, the outer layer is non latex condom, and the inner layer is latex condom.
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