According to a new report, researchers have officially identified a new brain disease that is very similar to Alzheimer's disease, named it and given the diagnostic criteria, according to the US media. So what will new dementia look like?
According to the us interesting science website on April 30, the disease will be named late. Late has only recently been identified as a form of dementia, and this is the first time researchers have reached a consensus on the name of the disease and how to distinguish it from other brain diseases.
The latest report, published on April 30 in the Quarterly Journal of brain, is the product of a symposium on the disease sponsored by the National Institute on aging in the United States. The participants included researchers from more than 20 institutions in six countries.
US media said that due to the similar symptoms of late and Alzheimer's disease, there may have been cases of late mistaken for Alzheimer's disease. Recognizing that these are two different diseases will boost research on both diseases, the authors said.
Nina & middot; Silverberg, program director of the Alzheimer's disease center of the National Institute on aging and co chair of late seminar, said, "the ultimate goal & hellip; & hellip; is to either prevent or at least treat the 'causes and symptoms' of' two brain diseases', whether it's Alzheimer's disease or late.
The report points out that there is an 'urgent need' to study late, because there is still too much to understand about this disease, including how to improve the level of diagnosis and identify risk factors, as well as the prevention and treatment of this disease.
The hallmarks of Alzheimer's disease are the accumulation of & beta; - amyloid plaques and tangles formed by another protein in the brain called tau.
But researchers recently found that not everyone suspected of Alzheimer's disease has these telltale signs in their brains, which means they are actually suffering from another disease.
In late cases, another misfolded protein, TDP-43, was accumulated in the brain, the report said. Late often affects the 'oldest person' in the population - more than 20% of people over the age of 85 show signs of the disease. But Silverberg said more research is needed to better understand how many people have the disease.
However, it is also mentioned in the report that the impact of late on public health is likely to be at least as serious as Alzheimer's disease.
Late affects many cognitive domains including memory, and ultimately affects daily activities. Late seems to worsen more slowly than Alzheimer's disease, but these two diseases may coexist, leading to a faster deterioration rate than only one of them.
According to the location of TDP-43 in the brain, late is divided into three 'stages' - the three regions of TDP-43 are amygdala, hippocampus and middle frontal gyrus.
At present, late can only be diagnosed at postmortem autopsy. But the authors of the study say they hope the new report will promote research on biomarkers of the disease so that doctors can diagnose the disease before a patient dies and study it in clinical trials. Finding a biomarker for the disease is also important for Alzheimer's research, the authors say, because it allows researchers to tell which disease a patient is suffering from in the living time zone.