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Must rabies vaccine be given five injections? How to do with missing rabies vaccine

If you are bitten or scratched by cats and dogs in your life, many people will get rabies vaccine. It is said that rabies vaccine needs five injections. Is that true? What are the precautions for getting rabies vaccine? Let's get to know.

Why five injections of rabies vaccine

Because rabies vaccine is an inactivated vaccine, it needs to be inoculated many times to complete the whole immune protection. Generally, it takes 5 injections to achieve the best immune effect. In the process of producing immune response, each vaccination will further activate the immune system to produce more antibodies, so it is required to give 5 injections of vaccine within a month, in order to produce antibodies and eliminate the virus as soon as possible.

The first three injections stimulate the body to produce antibodies as soon as possible. After three injections, the body can produce antibodies reaching the protection level, but the maintenance time is not long. The second two injections belong to the enhanced immunity, which is to maintain the persistence and titer level of antibodies. After five injections of immunization, the antibody level can reach the protection level at least in half a year, and there is no need to vaccinate again for mild bite.

Must rabies vaccine be given five injections

Of course, it does not mean that five injections must be given, but the specific situation of the bite. Generally bitten or scratched, the bite is more serious, the wound is more deep, must be rabies vaccine inoculation, because rabies virus is the existence of incubation period, need to be injected immediately within 24 hours, usually need to be injected five needle vaccine, because rabies virus immunogenicity is relatively poor, the general human body is unable to neutralize the virus So you need five injections to dilute the virus.

But this is related to the severity of the injury. If the patient is not bitten or scratched, and there is no obvious wound, there is no need to inject five injections of vaccine. Only three injections of vaccine can well inhibit the spread of the virus. In addition, due to the different doses of rabies vaccine from different manufacturers, some may be 3 injections.

In short, under normal circumstances, five injections of rabies vaccine are given for continuous stimulation to ensure the production of antibodies against rabies virus, so that the effect of the vaccine can be brought into full play, so as to well control the patient's condition. Specific vaccine related matters are best to follow the doctor's advice.

The time of five injections of rabies vaccine

Rabies vaccination interval is 0 (bitten day), 3, 7, 14, 28 days, it is best to be in strict accordance with the provisions of the time to injection, so as to better produce antibodies.

Tips: for healthy people without bite, 3 injections can be given in 0, 7 and 21 days. One needle was strengthened after one year, and then another every 1-3 years. For example, the staff with high risk of bite or chance of contact with virus in the epidemic area, such as veterinarian, animal feeding and management personnel, animal husbandry personnel, slaughtering personnel, rabies virus laboratory personnel, vaccine manufacturing personnel, medical staff of rabies patients, cave staff, as well as those who have frequent contact with other mammals, children, postmen and tourists in the epidemic area All patients were vaccinated with rabies vaccine.

Rabies vaccine missed hit how to do

Missed 1-2 days: make up in time

Usually, if the rabies vaccine missed a shot, the time is short, in 1-2 or so, timely replacement can, generally will not affect the entire immune effect.

Longer missed injection time: intensive injection / re inoculation

If the missed injection lasts for more than 2 days, it may be necessary to increase the dose of the injection, and if necessary, inject anti rabies immune serum to produce protective antibodies in time to avoid the attack of rabies;

The interval is long, and it may need to be re vaccinated according to the patient's immune condition.

Missed last injection: no need to repeat according to the situation

If the vaccination is 5 injections of vaccine, but missed the last shot, sometimes may not play it does not matter. Of course, it is still necessary to check in time in the hospital to see if there are antibodies, and to confirm whether the bitten animal is healthy, has no medical history, has been injected with rabies vaccine, etc.

However, if the patient is bitten seriously and the wound is deep, the last shot missed must be filled in time. After all, if rabies comes on, the death rate will reach 100%, so we can't take it lightly.

In short, rabies vaccine missing play to timely check antibody. Because the patient had missed rabies vaccine before, it is suggested that the later supplementary injection should be sent to the hospital in time to check whether the antibody has been produced, so as to ensure the effect of preventing immune disease.