now that the vaccine incident has attracted the public's attention, why don't even children let go of these black heart manufacturers? The flowers and future of the motherland are thus destroyed. The public is generally concerned about the impact of "record falsification in vaccine production" on the actual efficacy of the involved vaccine. However, if the "titer index" of DPT vaccine does not meet the standard, will it have adverse effects on children's health? What adverse reactions will children have if they are vaccinated with unqualified vaccine? Let's have a look.
1. Which enterprises and batches are involved in vaccines with unqualified titer index?
According to the information released by the State Food and Drug Administration on November 3, 2017, the potency index of DPT vaccine with the batch number of 201605014-01 produced by Changchun Changsheng Biotechnology Co., Ltd. and 201607050-2 produced by Wuhan Institute of Biological Products Co., Ltd. does not meet the standard.
2. How to query whether children have been vaccinated with DPT vaccine with unqualified titer index?
Parents or guardians of children can check the vaccination record of DPT on the children's vaccination certificate, compare it with the published vaccine manufacturer and batch number, and judge whether the unqualified DPT vaccine of corresponding batch number has been inoculated. You can also consult the vaccination unit, and the vaccination unit will assist in querying the batch number of the DPT vaccine to determine whether the unqualified DPT vaccine of the corresponding batch number has been inoculated. You can also call 12320 health hotline for consultation.
3. Will vaccination of DPT vaccine with unqualified titer index affect the immune effect?
The two batches of DPT vaccine were not qualified, which may affect the immune protection effect. The national health and Family Planning Commission and the health and family planning departments of Hebei, Shandong and Chongqing are organizing experts to evaluate the situation. According to the evaluation results, corresponding measures will be taken to properly handle the situation.
4. Is DPT vaccine with unqualified titer safe?
China food and drug inspection and research institute conducts safety index inspection on the vaccines submitted by enterprises for approval and issued one by one
The safety indexes of the two batches of vaccines meet the standards. The safety risk of the two batches of vaccines did not increase.
5. Will children suffer from pertussis, diphtheria and tetanus after vaccination?
Vaccination against pertussis is an effective measure to prevent diphtheria, tetanus and pertussis in children. According to the national immunization program, DPT vaccine needs to be vaccinated four times, one time at the age of 3, 4, 5 and 18 months respectively. Children who have completed four times of vaccination can get better protection effect. Relevant research shows that the efficacy of pertussis vaccine against typical pertussis is about 85%.
As a result, even children vaccinated against pertussis are at risk for a small number of people. The protective effect of DPT vaccine against tetanus in children is 80-100%. Four doses of DPT vaccine can provide effective protection for adolescents. The protective effect of DPT vaccine on diphtheria is better. The protective effect of more than three doses of DPT vaccine is about 95%.
6. What is the incidence of pertussis, diphtheria and tetanus in China?
The annual incidence of pertussis in China was 1 / 100000-2 / 100000 in the 1960s-1970s. Since the 1960s, we have been inoculated with DPT vaccine. Since 1978, we have incorporated DPT vaccine into the national immunization program. After the widespread use of DPT vaccine, the incidence of DPT vaccine has declined significantly. Since 2008, the reported incidence of pertussis in China has been controlled below 0.5/100000.
In addition to neonatal tetanus in China, tetanus in other populations is not a legally reported infectious disease.
Since 2007, no diphtheria cases have been reported in China.
7. What are the clinical manifestations of pertussis, diphtheria and tetanus?
Pertussis is an acute respiratory infectious disease caused by pertussis bacilli. The source of infection is pertussis patients, which is transmitted by droplets. The clinical symptoms were paroxysmal spasmodic cough, and there was a special "cockcrow" like high pitched sound when inhaled after coughing. The coughing symptoms lasted for 2-3 months. Most of the cases occurred in children aged & lt; 5, especially in infants aged & lt; 6 months.
Diphtheria is an acute respiratory infectious disease caused by Diphtheria Bacillus. Its clinical features are congestion and swelling of mucous membrane in nose, pharynx and larynx, and formation of gray pseudomembrane, which leads to respiratory disorders and toxic symptoms caused by exotoxin.
Tetanus is an infectious disease caused by tetanus bacillus. Tetanus is common in soil. During skin trauma, tetanus spores can be brought into the wound. Under anaerobic environment, tetanus bacteria can produce tetanus toxin, causing tetanus specific muscle rigidity and paroxysmal spasm. In the case of skin trauma, especially in the presence of the above-mentioned infection factors, we should go to the hospital in time. The doctor will choose a reasonable treatment plan according to the trauma situation, and use tetanus toxoid or / and tetanus immunoglobulin for post exposure prevention if necessary.