Summer heat, in order to avoid heatstroke, many people will bring some herbs such as Huoxiang Zhengqi water. However, a recent one said that "Huoxiang Zhengqi water can't be eaten with cephalosporin, or it will cause severe poisoning and death" but the news spread wildly in the circle of friends. Can Huoxiang Zhengqi water and cephalosporin be eaten together? What's the harm of eating together?
Huoxiang Zhengqi water containing alcohol can't be eaten with cephalosporin!
Xu Lianghui, a clinical pharmacist in the traditional Chinese medicine room of Hangzhou first people's Hospital, said: 'although the expression is not rigorous, Huoxiang Zhengqi water can't be eaten with cephalosporin. '
Huoxiang Zhengqi preparation has the functions of relieving exterior dampness, regulating qi and regulating middle, and is used for cold caused by external wind cold, internal dampness stagnation or summer dampness. Clinically, Huoxiang Zhengqi preparation is commonly used in the prevention and treatment of gastrointestinal cold and heatstroke.
However, Huoxiang Zhengqi water contains 40-50% ethanol (commonly known as alcohol). When taking cephalosporins or metronidazole and other antibacterial drugs, even a small amount of alcohol or alcohol containing drinks may cause adverse reactions such as headache, vomiting, palpitation, dyspnea, etc. in severe cases, symptoms such as respiratory depression, myocardial infarction, shock, and acute heart failure may occur. This reaction is called the sulfur like reaction of abstinence, also known as the disulfiram like reaction.
Huoxiang Zhengqi other non-alcoholic preparations will not cause similar harm
The chemical structure of these antibacterial drugs contains a structure similar to that of disulfiram, and its effect is similar to that of alcohol abstaining sulfur. Therefore, once patients drink alcohol after taking antibacterial drugs containing alcohol withdrawal sulfur, this component will prevent the oxidation of acetaldehyde, a harmful substance in alcohol, from being metabolized into water and carbon dioxide, resulting in an increase in the concentration of acetaldehyde in the human body, followed by alcohol withdrawal sulfur like reaction and discomfort symptoms.
At present, in addition to Huoxiang Zhengqi water, there are oral liquid, soft capsule and dropping pill. Other non-alcoholic preparations of Huoxiang Zhengqi will not cause disulfiram like reaction with cephalosporin.
These drugs can't be used with cephalosporins either
According to reports, at present, the commonly used oral drugs containing ethanol include Huoxiang Zhengqi water, shidishui, compound liquorice oral solution, zuocarnitine oral solution, ergot yinting caffeine oral solution, etc. External preparation Zhenggu water, qushangxiaozhong tincture, jingtongxiaotincture, Shujinhuoluo liquor, shexiangshuhuo liniment, shexiangqutong liniment, Xiaozhongzhitong tincture, etc., as well as the drugs containing ethanol mentioned in the manual. Both these drugs and cephalosporins may cause disulfiram like reactions.
The doctor suggested not to drink within 7 days after stopping cephalosporin
The doctor reminded that from a safety point of view, if taking cephalosporin drugs, do not drink or take drugs containing ethanol within 7 days after drug discontinuation, such as Huoxiang Zhengqi water, etc., and also avoid external use of drugs containing ethanol; if taking drugs containing ethanol, it is better to wait two days before taking cephalosporin drugs to avoid discomfort of the body.
In case of disulfiram like reaction, patients with mild reaction can subside by themselves without special treatment, and the symptoms will be relieved or disappear after stopping alcohol; in case of serious poisoning reaction, they must be treated immediately by medical treatment.
There are many medicines for heatstroke
In fact, there are many cheaper and safe medicines to prevent heatstroke, such as Fengyoujing and qingliangyou, which should be used with caution by allergic persons, infants and pregnant women; oral Chinese medicine includes Kelisha capsule, jinyinhualu, which can also be used to make tea with honeysuckle, mint, Huoxiang, lotus leaf, chrysanthemum and other pieces of Chinese medicine.