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What happens to the death of rabies vaccine in 3 days? The truth behind it shocked the circle of fri

What happens to the death of rabies vaccine in 3 days? The truth behind it shocked the circle of friends! In early April this year, a 29 year old man in Suzhou went to the outpatient department of Caohu people's Hospital in Xiangcheng District of Suzhou to inject rabies vaccine because he was scratched by a kitten. Who would have thought that three days later, he died because of ineffective rescue of unknown symptoms. The family was very angry about his bizarre death and wanted to talk to the hospital. Is it the problem of vaccine or the fault of hospital operation?

On April 4 this year, Wang Xinwei (pseudonym), who worked in Suzhou, was scratched by a domestic vaccinated kitten; On April 5, Wang Xinwei injected rabies vaccine in the outpatient department of Caohu people's Hospital, Xiangcheng District, Suzhou. In the next two days, Wang Xinwei had chest pain, body pain, fever, diarrhea and low blood pressure.

On April 8, Wang Xinwei was unconscious and lost spontaneous breathing. He was sent to the First Affiliated Hospital of Suzhou University for first aid. Finally, he suffered from systemic organ failure and died at about 5:30 p.m. that day.

It is understood that Wang Xinwei injected the freeze-dried rabies vaccine for human use produced by Liaoning Chengda biology Co., Ltd. the production date is May 5, 2018, the validity period is May 4, 2021, and the batch number is 201805102. Liaoning Chengda is currently the largest domestic rabies vaccine manufacturer in China.

After the incident, the family members reported the above situation to the local regulatory authorities. On May 21, the staff of Suzhou food and drug administration went to Caohu people's Hospital of Xiangcheng District to seal up the remaining two vaccines of Wang Xinwei, and the remaining 13 vaccines of the same batch were also sealed up. At present, these vaccines will be sent to Beijing for testing.

Wang Xinwei's wife Zhang Jie (a pseudonym) told reporters that her husband's sudden death has been unacceptable to her and her family. Wang Xinwei is only 29 years old. According to the physical examination report in February this year, his physical condition is not abnormal.

Zhang Jie suspected that there was a problem with the injected vaccine. The reason for this is that after Wang Xinwei had discomfort symptoms such as chest pain and diarrhea, he went to the emergency department of Caohu people's hospital. The inspection report showed that Wang Xinwei had allergic diarrhea.

"After seeing this checklist, I told the doctor that he had been vaccinated against rabies on the 5th, and the doctor denied that it was a vaccine problem." Zhang Jie told reporters.

At about 7 a.m. on April 8, seeing that my husband was not getting better, Caohu people's Hospital suggested that we transfer to a larger Xiangcheng people's hospital. Xiangcheng people's hospital gave the diagnosis of suspected cardiac dissection. The hospital suggested that if we want better surgical treatment, we should go to the First Affiliated Hospital of Suzhou University. After arriving at the First Affiliated Hospital of Suzhou University at about 10 a.m. on April 8. The hospital issued a critical notice. " Zhang Jie recalled the treatment scene at that time.

A critical notice provided by Zhang Jie from the First Affiliated Hospital of Suzhou University shows that Wang Xinwei's clinical diagnosis is suspected of septic shock and aortic dissection.

According to Zhang Jie, the diagnosis of Caohu people's hospital was allergic diarrhea; Xiangcheng people's Hospital considers it as cardiac dissection and gives two options of conservative treatment or operation; The doctors of the First Affiliated Hospital of Suzhou University denied the cardiac dissection and suspected that it was an explosive blood disease.

"This is most likely due to allergic reactions to rabies vaccine." Zhang Jie said, 'and it is impossible to have an outbreak of rabies within three days. We think it is organ failure caused by allergic reaction. But until my husband died, the hospital did not give the specific reason for our death. "

On May 24, the reporter consulted the staff of the medical department of Liaoning Chengda biology Co., Ltd. on the relevant situation of vaccine allergy. The other party said that the usual clinical manifestations of vaccine allergy are Henoch Schonlein purpura, red rash or bleeding points under the skin. The staff member also said that diarrhea is also possible, but it is not caused by allergy, but the intestinal disorder caused by the stress response of the immune system to the vaccine.

The staff member said that the rabies vaccine is an inactivated vaccine, which is the same as the allergic symptoms that may be caused by all inactivated vaccines. There is no need to worry too much about safety. Even if there is an allergy, it will not be a big problem.

The reporter verified Wang Xinwei's deathbed with the First Affiliated Hospital of Suzhou University. The staff in charge of answering the phone in the outpatient department of the hospital said that due to the long time interval and many patients, they were unable to give a reply.

Wang yuedan, deputy director of the Department of immunology of Peking University, pointed out to reporters that whether it is caused by the vaccine needs to wait for the verification results given by the drug regulatory department. " However, from the description, there are no typical allergic symptoms, but mainly gastrointestinal symptoms. This is not a common situation in the process of rabies vaccination, and there are no autopsy and pathological anatomy results. From the current situation, it is difficult to say that it is caused by the vaccine. " Wang yuedan said.

Events after Wang Xinwei registered the vaccine:

At about 10:00 p.m. on April 4, 2019, he was scratched by a vaccinated cat;

At about 10 a.m. on April 5, 2019, he went to the outpatient department of Caohu people's Hospital in Xiangcheng District to inject rabies vaccine;

On the afternoon of April 5, 2019, he began to feel sore and accompanied by fever;

On the morning of April 6, 2019, I went to Caohu people's Hospital in Xiangcheng District to consult a doctor. The doctor told me that it was normal and that I could take some antipyretic drugs;

On the evening of April 6, 2019, diarrhea began and lasted all night;

At about 8 p.m. on April 7, 2019, I went to the emergency department of Caohu people's Hospital in Xiangcheng District and felt chest tightness, hypothermia and low blood pressure;

At about 7 a.m. on April 8, 2019, Caohu people's Hospital of Xiangcheng District suggested going to Xiangcheng District People's Hospital for treatment

Before 8:00 a.m. on April 8, 2019, the patient arrived at Xiangcheng people's hospital. The patient developed chest pain, and the doctor gave the diagnosis of suspected cardiac dissection.

At about 10 a.m. on April 8, 2019, after arriving at the First Affiliated Hospital of Suzhou University, the doctor denied the diagnosis of cardiac dissection and suspected that it was explosive blood disease;

He died around 5:30 p.m. on April 8, 2019.

Precautions for rabies vaccination:

1. During vaccination, you should pay attention not to drink alcohol, strong tea and coffee; Don't eat stimulating food, such as pepper, onion, garlic and so on.

2. Try to avoid catching cold, cold, strenuous exercise or excessive fatigue.

3. If pregnant women are bitten, they should also be injected with rabies vaccine in time.

4. Injection of rabies vaccine should go to a regular hospital or CDC with rescue equipment. In case of allergic reaction, it can be rescued in time.

5. If the vaccine is found to have an unshakable clot, or discoloration, or a crack in the bottle, or the liquid vaccine has been frozen, do not inject it.

6. For rabies vaccine, vitamins and anti infective drugs can be given at the same time. At the same time, in order to avoid immune interference, patients should not be vaccinated with other vaccines as far as possible during rabies vaccine.