Cervical cancer is the most common gynecological cancer. The high incidence age of carcinoma in situ is 30-35 years old, and that of invasive carcinoma is 45-55 years old. It is an important disease affecting modern women, but many women do not find it because they do not often have physical examination. Recently, a major breakthrough has been made in a domestic research institute, which can directly detect cervical cancer by exhaling!
The reporter learned from Hefei Institute of material science of Chinese Academy of Sciences on October 23 that the medical physics center of the Institute has made progress in the research of rapid screening cervical cancer. Using the self-developed expiratory mass spectrometer, the researchers can directly measure the exhalation of a subject in 7 seconds.
The study was recently published in analytical and biological chemistry.
Cervical cancer is a common malignant tumor that seriously threatens women's health. There are more than 500000 new cases every year in the world, of which about one third are Chinese patients. Cervical cancer is also the third highest incidence of cancer among young and middle-aged women in China.
Common screening methods for cervical cancer mainly include cytology (Pap test) and human papillomavirus (HPV test), all of which require the invasion of instruments, and the detection of cells or viruses takes a certain time.
Breath detection has been a research hotspot in the field of diagnosis because of its safety, noninvasive, simple and high acceptance.
A real-time on-line expiratory mass spectrometer has been developed by researchers of Hefei Institute of material science, Chinese Academy of Sciences. It can directly measure the exhalation of a subject in 7 seconds. Based on the breath test of 13 patients with cervical cancer and 34 healthy people, we found that the true positive rate and the true negative rate were 92.3% and 88.2% respectively.