How long can chronic myeloid leukemia live? What are the early signs? The occurrence of chronic myeloid leukemia is the partial segmental translocation of chromosomes 9 and 22, forming the BCR-ABL fusion gene, and the BCR-ABL protein in which this gene plays a role has tyrosine kinase activity, which will maliciously and continuously transmit the signal of proliferation, and finally lead to the occurrence of CML. Let's learn about it together
How long can chronic myeloid leukemia live
When leukemia was mentioned before, people soon realized that it was an incurable disease. However, with the development of science and technology and the research of medical technology, the fallacy that leukemia is an incurable disease is broken without attack. Even if leukemia can be treated, the family members of leukemia patients have been very concerned about the patient's life span. Many experts and scholars have also discussed how long leukemia patients can live, but it has been difficult to have a clear answer. In the process of treating leukemia, many factors are involved, such as treatment methods, nursing, physical condition, psychological problems and so on.
Treatment is the key to leukemia rehabilitation, but other factors can not be ignored. Generally speaking, how long you can live after suffering from leukemia mainly depends on its treatment and the patient's own physical and psychological conditions.
For example, chronic myeloid leukemia is one of the common diseases of leukemia, and this disease will eventually die of serious complications such as bone marrow fibrosis, acute leukemia, multiple organ failure, infection and bleeding. The situation of chronic lymphocytic leukemia is different. It is as short as one to two years and as long as five to ten years. During this period, some adverse changes will occur in the body.
For patients with advanced leukemia, it mainly depends on whether the treatment is appropriate and whether the patient's physical condition is good. The common treatment methods for advanced leukemia include, chemotherapy, bone marrow transplantation, traditional Chinese medicine treatment and so on. Bone marrow transplantation is the most effective method for the treatment of advanced leukemia, but it is expensive. Patients need to think twice.
Chemotherapy is the first choice for the treatment of leukemia. Chemotherapy must be selected first for both acute and chronic leukemia. In addition to the above leukemia treatment methods, we should also see whether the patient's own physical condition is good. Patients with strong physical fitness and resistance may live longer, and even recover after treatment; Patients with poor physique may live a short life and die because they can't bear the suffering treatment. After all, there are many factors affecting the life span of leukemia patients, which can not be generalized. Making a hasty conclusion may exert unnecessary pressure on patients.
Symptoms of chronic myeloid leukemia
clinical manifestation
1. Multiple population
Chronic myeloid leukemia is a relatively rare malignant tumor, accounting for about 0.3% of all cancers and 20% of adult leukemia; In the general population, about 1 to 2 people per 100000 suffer from the disease. Chronic myeloid leukemia can occur in people of any age, but it is common in people over 50 years old. The average age of onset is 65 years old. Men are more common than women.
2. Clinical stage
Chronic myeloid leukemia progresses slowly. According to the number of leukemia cells in bone marrow and the severity of symptoms, it is divided into three stages: chronic stage, accelerated stage and acute stage. Among them, about 90% of patients are diagnosed as chronic phase, and about 3% to 4% of chronic phase progress to acute phase every year.
3. Symptoms
Because the progress of chronic myeloid leukemia is relatively slow, many patients have no symptoms, especially in early patients. With the progress of the disease, leukemia destroys the normal hematopoietic function of bone marrow and infiltrates organs, causing obvious but nonspecific symptoms.
1. Anemia
Manifested as fatigue, dizziness, pale complexion or shortness of breath after activity;
2. Repeated infection and difficult to cure
Mainly due to the lack of normal leukocytes, especially neutrophils;
3. Bleeding tendency
Easy bleeding, bleeding, gum bleeding, stool bleeding and irregular menstrual bleeding, etc., caused by thrombocytopenia;
4. Weight loss and night sweats
Splenomegaly, unexplained weight loss and night sweats.