Middle school students squat for 10 minutes. What is muscle dissolution? Causes and symptoms of myol

Today, a news about "middle school students squatting for 10 minutes and muscle lysis" has attracted many people's attention. Many people don't know what muscle lysis means. What is muscle lysis? What are the factors causing muscle lysis? What are the symptoms of myolysis? This article has brought home the relevant introduction of muscle lysis. Let's have a look.

on August 30, Mr. Xu, a citizen of Tianjin, reported that his daughter was corporal punished by the head teacher at school and squatted for 10 minutes. The diagnosis certificate issued by Tianjin Children's Hospital showed that Mr. Xu's daughter was diagnosed with rhabdomyolysis. About 10000 yuan was spent before and after hospitalization. According to the latest response of Tianjin Hongqiao District Education Bureau, the school has apologized to the parents of the students concerned. As for whether the teachers will be dealt with, the incident is still under investigation. What does myolysis mean? Rhabdomyolysis syndrome, also known as myolysis, is an old and young disease. It is ancient because crush syndrome and its acute renal failure were first reported in the Sicilian earthquake in 1908. During the bombing of London in 1940, it was further reported and recognized. Non traumatic rhabdomyolysis was first reported in 1970, and it was realized that it can also lead to acute renal failure. It's young because most people can't understand the disease, and some people haven't even heard the name of the disease. Factors of muscle lysis

In fact, rhabdomyolysis syndrome refers to a syndrome of biochemical disorder and organ function damage caused by myoglobin and other substances entering the blood after rhabdomyolysis. There are many pathogenic factors of rhabdomyolysis syndrome, including genetic factors and acquired factors. The acquired factors include but are not limited to the following:

1. Excessive exercise: excessive exercise leads to the destruction of skeletal muscle, releasing cell contents into the blood and excreting them from the urine.

2. Trauma: muscle compression, long-term braking, electric shock and other factors.

3. High heat: self heating, high ambient temperature, etc.

4. Endocrine and metabolic disorders: hypokalemia, hypocalcemia, hyponatremia, hypernatremia, ketoacidosis, hyperosmolar coma, etc.

5. Drugs and poisons: alcohol, cocaine and other hallucinogens, glucocorticoids, central nerve inhibitors, neuromuscular blockers, etc.

6. Infection: viral infection, such as influenza virus A or B (the most common), Coxsackie virus, herpes virus, etc. Bacterial infections, such as Legionella (the most common), Salmonella, etc.

7. Inflammatory or immune diseases: pancreatitis, tumor, dermatomyositis, polymyositis, etc.

symptoms and manifestations of myolysis

Once the disease occurs, the body will have a series of symptoms, which will directly lead to death. The clinical manifestations are generally as follows:

1. Inflammatory reaction: fever, general fatigue, increased proportion of leukocytes and / or neutrophils.

2. Affected muscle performance: muscle pain, tenderness, swelling and weakness; On MRI, the affected muscles were swollen and the T1 and T2 phases were high signal.

3. Characteristic manifestations of myocyte necrosis: increased serum Myozyme, myoglobinemia and myoglobinuria (urine appearance: tan or red grape wine color; urine routine: benzidine test shows positive blood and often proteinuria; sediment test: no red blood cells or a small amount of red blood cells and granulocyte type)

Once rhabdomyotic syndrome occurs, if it is not treated in time and allowed to develop, it is very easy to lead to complications, such as acute renal tubular necrosis (requiring volume resuscitation with saline and mannitol, alkalization of urine, hemodialysis or continuous hemofiltration, taking drugs to reduce the further development of the kidney: antioxidants, dopamine, iron chelators, etc.), hypovolemia, hypoproteinemia and DIC (disseminated intravascular coagulation), intermuscular space syndrome, etc

Strictly speaking, rhabdomyolysis can not be called a disease, but a syndrome composed of a series of symptoms, and the probability of this series of symptoms is not very high, and this problem will not occur in most cases. However, the exercise mode and intensity can not be ignored, and daily exercise must be appropriate.