Recently, scientists in the United States say that the HIV virus of live mice DNA was successfully eradicating by gene editing technology for the first time, which means that AIDS is expected to be cured.
Recently, American researchers successfully eliminated the HIV virus in the DNA of living mice for the first time. The experiment was published in the journal Nature communication by researchers from Temple University and the University of Nebraska. Study participant Dr. Camille said that this is a major breakthrough and the first proof that HIV is a curable disease.
It is reported that at present, there are about 37 million HIV carriers worldwide, and HIV is currently being treated with antiretroviral therapy. This therapy can inhibit virus self replication, but it can not be completely eliminated. If the patient stops treatment, the virus will continue to replicate itself.
Researchers can now destroy the virus in 'anthropomorphic' mice. They injected human bone marrow into mice to mimic the human immune system, and used gene editing and drugs to fight the virus. Of the 21 mice tested, 9 were removed, the researchers said. At present, they are testing the effect of this combination therapy on primates. The researchers' goal is to obtain the approval of the U.S. Food and drug administration to conduct phase 1 clinical trials in humans by 2020.
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'London patient' or second AIDS healers? He has received hematopoietic stem cell transplantation
According to CNN (CNN) reported on March 5th, the latest medical research report shows that in Britain, an AIDS patient has been cured after treatment, he may become the world's second completely cured AIDS patients. The news' encouraged 'the medical community. Some medical experts said that the treatment experience was worth promoting, but others said that the treatment results should be treated with caution.
CNN said that British Nature magazine published a paper on 5, a AIDS patient known as' London patient 'has been treated for 18 months without HIV detection. He may become the second AIDS patient who has been cured after the 'Berlin patient'. London patient "is a male, the specific identity is unknown, he was found in 2003 infected with HIV, in 2012 began to receive drug treatment, later in 2012 was found to have Hodgkin lymphoma, in 2016, he began to receive chemotherapy and hematopoietic stem cell transplantation, 16 months after stopping treatment, since then, 18 months have not detected the AIDS virus.
So far, the world's only recognized cure for AIDS is the "Berlin patient" named Timothy ·. Brown, who received chemotherapy and stem cell transplantation in Berlin in 2007, has not detected HIV since then. Gupta, a professor of infection and immunology at University College London, said that after similar treatment, the condition of AIDS in London patients was relieved, proving that the previous' Berlin patient 'is not a case. Stem cell transplantation therapy has cleared the HIV virus.
Original title: gene editor to remove HIV, AIDS is expected to be cured, 9 mice were successfully removed virus