Super fungi break out in many places in the United States. What is super fungi
4hw.com.cn: Recently, super fungi broke out in the United States, and according to experts from authoritative institutions, the death rate of this fungus is as high as 60%, so what is super fungi? Let's take a look,
"Up to now, China has confirmed 18 cases of super fungal clinical infection, which is called & lsquo; Super fungus & rsquo; It refers to Candida. We are still monitoring continuously, but on the whole, there is no explosive epidemic infection like that in the United States. "
The New York Times reported on April 6 that when Mount Sinai Hospital in New York City performed abdominal surgery on an elderly man last May, it was found that he was infected with a 'mysterious and deadly' fungus, and the hospital quickly isolated him in the intensive care unit. The man eventually died after 90 days in hospital, but the deadly fungus survived tenaciously. Many parts of the ward were invaded. The hospital disinfected the walls, beds, doors, sinks and telephones, and even removed some ceilings and floors. At present, this multidrug-resistant fungus called Candida auriculata is popular in 12 states such as New York, New Jersey and Illinois.
"Super fungi can survive on the skin of patients and medical staff and the surface of hospital facilities for a long time. If the infection control measures are not effective, it is easy to lead to explosive infection in the hospital." Wang Hui, director of the Department of laboratory science of Peking University Medical Department and director of the laboratory department of Peking University People's Hospital, said that the culprit of the outbreak of super fungal infection in the UK in 2018 was a shared thermometer.
"According to the existing literature, most infected people have unexplained high fever, ineffective drug treatment, and accompanied by various manifestations such as organ failure and respiratory failure." Liao Wanqing said. In 2018, the first case of clinical infection of Candida auriculae was found in China. The first strain of Candida auriculae in China was isolated from a 76 year old patient. This study was jointly completed by a team led by Wang Hui and Huang Guanghua, researcher of the State Key Laboratory of mycology, Institute of Microbiology, Chinese Academy of Sciences.
Since then, Shang Hong, director of the laboratory department of the First Affiliated Hospital of China Medical University, and her team identified 15 hospitalized patients infected with Candida. According to Liao Wanqing, the Academy of Military Medical Sciences also identified two cases. " So far, Chinese mainland has identified 18 cases of clinical infection of Candida albicans, and we are still monitoring it.
The source of Candida auriculalis is still unclear, whether it is an environmental fungus or a human symbiotic fungus. Researchers generally believe that this is a newly evolved new species with the ability to quickly adapt to the human host environment. It mainly causes blood infection, and the death rate is as high as 60%.
Under the microscope, there is no significant difference between Candida auriculata and other Candida, but they usually have multiple drug resistance. Some strains have high drug resistance to three kinds of antifungal drugs commonly used in clinic. This super fungus is the most lethal to the immature or damaged immune system, including newborns and the elderly, smokers, diabetics and autoimmune diseases.
Recently, the U.S. Centers for Disease Control and Prevention (CDC) has included Candida in the list of "emergency threats". According to the latest report on its official website, the number of infected cases in the United States has risen to 587, and nearly 50% of infected people have died within 90 days. According to Liao Wanqing, by 2017, 24 countries around the world had an explosive epidemic of Candida albicans, including Japan, the United States, the United Kingdom, Spain, India and other countries.
In response to this emerging public health problem, the long march hospital held a seminar on the morning of April 9. Huang Guanghua, who was invited to make a report, explained that candidiasis in the ear will not have a great impact on healthy people. Fungal infection mainly occurs in hospitals and is concentrated in people with low immunity, such as ICU Wards. Mass epidemics in the United States also occur in hospitals.
The traditional biochemical identification methods are difficult to identify super fungi. At present, mass spectrometry and molecular biology are mainly used. According to Huang Guanghua, the main reason for the delay in the report of clinical infection cases of super fungi in China may be technical problems. "Mass spectrometry is not very common outside China's top three hospitals, and the possibility of missed detection cannot be ruled out."