With the development of the times and the improvement of people's living standards, coffee has become a popular drink. Most people drink coffee because of its mellow taste and refreshing effect, but coffee also has medical value. Do you know? Many people say that coffee can prevent cancer. Is this true? Let's talk about the relationship between coffee and cancer and the benefits of drinking coffee. If you like coffee, come and have a look. Relationship between coffee and cancer
1、 Benefits of coffee
We have said the benefits of coffee many times from the perspective of the coffee industry. Today, I forwarded an article from the medical community. It professionally discusses the relationship between 'coffee and various cancer prevention and treatment'. I'm glad to see that coffee is so powerful! In fact, coffee has always been the darling of medicine from reducing the risk of death to reducing the risk of certain cancers and diabetes and reducing the risk of depression and Parkinson's disease, but you don't know.
1. Coffee can reduce the risk of colorectal cancer
A recent study reported on cancer Epidemiol biomarkers prev by Stephanie L. Schmit of Norris comprehensive cancer center of the University of Southern California has deepened people's love for coffee - coffee can reduce the risk of colorectal cancer by 26%.
This is a population-based molecular epidemiology study of colorectal cancer in northern Israel. The researchers developed a validated, semi quantitative coffee intake frequency questionnaire for 5145 patients with colorectal cancer and 4097 healthy people without a history of colorectal cancer.
After adjusting for known risk factors, moderate coffee consumption (1 to 2 servings a day) reduced the risk of colorectal cancer by 26%, according to research data. With the increase of coffee consumption, the risk of colorectal cancer gradually decreases, which is obvious in both colon and rectal cancer.
Surprised! Caffeine doesn't work alone. The researchers said, 'coffee contains a variety of ingredients that promote colorectal health, caffeine and polyphenols have antioxidant effects, melanin can promote colonic peristalsis, and diterpenes can resist oxidative stress damage.'
2. Coffee reduces cancer recurrence in patients with colon cancer
Researchers at Dana Farber Cancer Institute published a study in the Journal of clinical oncology that regular coffee drinking can significantly reduce tumor recurrence and improve the survival rate of patients with stage 3 colon cancer.
The study followed the dietary patterns of 953 colorectal cancer patients who received chemotherapy for 6 months. They found that patients who drank four or more cups of coffee a day (about 460 mg caffeine) had a 42% lower risk of cancer recurrence than those who did not drink coffee. During follow-up, those who drank four or more cups of coffee regularly had a 33% lower chance of dying of cancer or any other cause than those who did not drink coffee.
Further analysis showed that the lower cancer risk was caused by the caffeine absorbed by patients, rather than the amount of other components of coffee.
3. Coffee reduces the risk of liver cancer
Researchers from the Ministry of clinical science and public health of the University of Milan and the Mario Negri Institute of pharmacology in Milan once reported in the Journal of clinical gastroenterology and Hepatology that the intake of any kind of coffee may reduce the risk of hepatocellular carcinoma (HCC) by 50% (the reduction range depends on the intake).
The report examined 16 studies conducted between 1996 and 2012, with a total of 3153 cases. The positive role of coffee in preventing liver cancer may be attributable to the effect of coffee on the prevention of diabetes, and diabetes is one of the causes of liver cancer, the researchers said. Another possibility is that coffee can prevent liver cirrhosis and has a beneficial effect on enzymes in the liver.
However, it may also affect the statistical results because patients with hepatocellular carcinoma generally avoid drinking coffee. Therefore, it is uncertain whether caffeine plays an additional role in the prevention of liver cancer.
4. Coffee reduces the risk of melanoma
The study published in the Journal of the National Cancer Institute on January 20, 2015 shows that drinking more than four cups of coffee a day can reduce the risk of skin cancer by 20% in ten years.
The study comprehensively observed 447000 subjects and involved 124 food questionnaires. The subjects were 50 to 71 years old and had no cancer at the beginning of the study. During more than ten years of research, more than 2900 subjects developed malignant melanoma and more than 1900 subjects developed another kind of skin cancer: melanoma in situ.
Excluding factors such as age, diet and family history, only considering the relationship between caffeinated coffee and melanoma, more than four cups of coffee a day can reduce the risk of skin cancer by 20% in ten years.
Theoretically, various components in coffee have been shown to affect a considerable number of molecular pathways that can reduce the risk of UV related skin cancer. But such a large sample study with humans as the experimental object is still very convincing.
5, coffee can inhibit breast cancer growth.
Researchers at Skane University Hospital in Lund University in the United Kingdom have published findings in the Clinical Cancer Research magazine. Women who are diagnosed with breast cancer and treated with tamoxifen can drink coffee to inhibit tumor growth and reduce the risk of recurrence.
In this study, 1090 patients diagnosed with primary invasive breast cancer in Sweden were assessed for two substances commonly produced in Swedish coffee: caffeine and caffeic acid, and their relationship with tumor characteristics and disease-free survival.
The study showed that women who drank at least two cups of coffee every day had half the risk of breast cancer recurrence in women who drank at least two cups of coffee per day, half of the women who drank two cups or less, and had a smaller tumor size and a lower proportion of hormone dependent tumors.
The researchers believe that caffeine and caffeic acid can block the progress of cell cycle and enhance cell death, so as to enhance the effect of tamoxifen treatment.
6. Coffee reduces the risk of head and neck cancer
The investigation of head and neck cancer by Aichi Cancer Center in Japan found that people who drink more than three cups of coffee a day have a 40% lower risk of head and neck cancer than those who drink less than one cup.
It will reduce the risk of death, reduce the risk of certain cancers and diabetes, and reduce the risk of depression and Parkinson's disease. Coffee seems to have become the 'pet' of medicine.
However, there seems to be no definite answer to the question of coffee. Although most studies show that the benefits of coffee outweigh the disadvantages for most people, no researchers are willing to give the hint of 'please enjoy coffee'.
The most conservative statement is: if you are a coffee drinker and are receiving some cancer treatment, don't stop drinking. Healthy people who have no habit of drinking coffee may as well cultivate the habit of drinking coffee from now on.
2、 How much coffee should I drink every day?
Coffee has many advantages, but everything has a limit. How much coffee do you drink every day? No one can say. Let's look at scientific research!
Professor Hu of Harvard School of public health and his colleagues conducted a large study, suggesting that we drink coffee every day in subjects who never smoke ≤ The risk of all-cause mortality decreased by 6%, 8%, 15% and 12% in subjects with 1 cup, 1-3 cup, 3-5 cup and > 5 cup, respectively. The decrease of mortality was mainly related to the decrease of cardiovascular mortality, nervous system disease mortality and suicide mortality. The study was published in the journal Circulation on November 16, 2015.