Heart damage from chemotherapy may be due to leaking pipes Known to damage heart tissue, the anticancer drug sunitinib, knocks out cells to seal blood vessels. May 29, Amgen and colleagues of Vishnu biotechnology company reported that in the case of peeling off microvascular pericytes in heart tissue There are no mucinous cells in the sheath that double as much fluid as possible permeates from the microvasculature.
Researchers say the leaking fluid may explain why as many as 28 percent of sunitinib treated cancer patients with heart disease.
The team's report also said there might be another way to solve the pipeline problem. Thalidomide, a well-known molecule that causes birth defects, is now used to treat cancer and protect perivascular cells from slaughtering sunitinib.
Metrology lab cell culture cycle only sunitinib kills cells, but gives him 'Science Translational Medicine chintalgattu'.
Tiny blood vessels or microvessels, called perivascular cells, are often coiled around to keep them healthy and to stop leaks, such as rubber patches that stick to bicycle tubes.
The researchers examined both treated and untreated mice and found that the two drugs did not seem to do any harm When the researchers transplanted human cancer tissue into mice and treated them with two drugs, the animals' tumors shrank and their hearts pumped normally.